CHARACTERIZATION OF CONSULTATIONS REQUESTED FOR PATIENTS WITH ELEVATED BLOOD EOSINOPHILS: A TERTIARY IMMUNOLOGY AND ALLERGY CLINIC EXPERIENCE

Objective: Blood eosinophilia has become a common laboratory abnormality and its characterization poses dilemma for physicians. As result, physicians often consult specialists in immunology allergy order to evaluate patients with high eosinophils, the general assumption of an underlying allergic or immunologic cause. However, there is little data literature regarding consultations requested from clinics because eosinophilia. This study aimed clinical demographic characteristics who were consulted clinic detail etiologies Methods: The medical records 1366 evaluated retrospectively, 143 investigated. Results: median (range) eosinophil count was 2456 cells/ mm3 (520-42920). 86 (60.1%) classified as mild (500 1500 cells/mm3 ), 44 (30.8%) moderate (1500 5000 13 (9.1%) severe (≥5000 ) most frequently departments chest diseases (37.1%), internal medicine (34.2%), dermatology (14.7%), respectively. While symptoms at presentation cough, dyspnea, pruritus, rhinitis, gastrointestinal symptoms, 49 (34.3%) asymptomatic. mean±SD vitamin B12 tryptase levels 424.2±240.5 pg/mL, 4.48±1.76 ng/mL, total IgE level 150 IU/mL (1.5-9464). Atopy was identified 26.6% (n=38) patients. Among patients, no diagnosed myeloproliferative lymphocytic variants hypereosinophilic syndrome (HES), eight idiopathic HES. causes asthma rhinitis (n=20), 30 had non-allergic causes. Conclusion: Although parasitic infections are first that come mind when detected patient, specific anamnesis advanced diagnostic tests differential should be performed detect other accompanying conditions apart these diseases.